- Follow-up of Hepatocellular Carcinoma After Transarterial Chemoembolization; The Concordance of Contrast Enhanced Ultrasonography and Lipiodol CT
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Gene Hyun Bok, Soung Won Jeong, Jae Young Jang, Sae Hwan Lee, Sang Gyune Kim, Sang-Woo Cha, Young Seok Kim, Young Deok Cho, Hong Soo Kim, Boo Sung Kim
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J Liver Cancer. 2014;14(2):115-119. Published online September 30, 2014
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DOI: https://doi.org/10.17998/jlc.14.2.115
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Abstract
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- Background/Aim
s: The aim of this study is to evaluate the concordance of contrast-enhanced
ultrasonography (CEUS) and lipiodol computed tomography (L-CT) for the assessment of
viable hepatocellular carcinoma (HCC) after transarterial chemoembolization (TACE). Methods We retrospectively reviewed the post-TACE CEUS and L-CT images of 65
consecutive HCCs in 41 patients to assess the presence of viable tumor tissue. Forty-seven
HCCs in 31 patients that underwent post-TACE L-CT within 4 weeks of the CEUS examination
were included. The degree of concordance between CEUS and L-CT and factors related to
concordance were analyzed. Results The overall concordance of CEUS and LDCT was 78.7% (37/47). The concordance with
L-CT for viable tumor and non-viable tumor tissue on CEUS was 95.2%, and 65.4% respectively
(P<0.013). Diffuse tumors had a tendency for non-concordance (P=0.066). Although 3 of 4
lesions located in the hepatic dome were non-concordant, the sample size was too small to
establish significance. The mean tumor size for concordant and non-concordant tumors was
2.9 and 3.0 cm, with no significant difference. Conclusions Although the concordance of CEUS and L-CT for viable tumor tissue was
high, the concordance for non-viable tumor tissue was relatively low. Prospective studies
using angiography as a gold standard should be performed in the future. (J Liver Cancer
2014;14:115-119)
- A One cm Sized Intrahepatic Cholangiocarcinoma in a Patient with Chronic Hepatiits B Misdiagnosed as Hepatocellular Carcinoma
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Gene Hyun Bok, Soung Won Jeong, Jae Young Jang, Kwang Yeun Shim, Sae Hwan Lee, Sang Gyune Kim, Young Seok Kim, Hong Soo Kim, Boo Sung Kim, So Young Jin, Sung Sook Hong, Yong Jae Kim
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Journal of the Korean Liver Cancer Study Group. 2012;12(1):23-27. Published online February 28, 2012
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Abstract
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- Morphologically, intrahepatic cholangiocarcinoma (ICC) presents as a parenchymal mass, and it is occasionally resectable and
potentially curable. In some cases, differentiation from other hepatic neoplasms such as metastatic lesions and hepatocellular
carcinoma (HCC) can be extremely difficult, both clinically and histologically, and definitive diagnosis often needs correlation
with clinical and radiologic finding.Contrasted computed tomography (CT) is useful in the diagnosis of ICC and in determining
the extent of tumor involvement. Although the majority of liver tumors can be diagnosed by modern imaging modalities such as
contrast CT, some cases of ICC show tumor enhancement in the arterial phase the same as that in HCC, or a biliary dilatation
without stenosis by intraductal tumor growth. Differences in these patterns of tumor enhancement and status of the bile ducts in
ICC may also reflect differences in cellular characteristics, clinical features, and prognosis after treatment. We present a case of a
small ICC showing similar clinical and radiologic characteristics to HCC.
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